Bathar
4-Hydroxy-D-(-)-2-phenylglycine
Synonyms: (R, S) -3HPG; 4-hydroxyphenylglycine; 4-hydroxyphenylglycine hydrobromide, (+-) -isomer; 4-hydroxyphenylglycine hydrochloride, (R) -isomer; 4-hydroxyphenylglycine perchlorate, (+-)-isomer; 4 -hydroxyphenylglycine, (+-) -isomer; 4-hydroxyphenylglycine, (R) -isomer; 4-hydroxyphenylglycine, (S) -isomer; 4-hydroxyphenylglycine, 2,4-dimethylbenzenesulfonate, (+ -) -isomer; 4-hydroxyphenylglycine , 2,4-dimethylbenzenesulfonate, (R) -isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (+ -) -isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (S) -isomer; 4-hydroxyphenylglycine, salann 4-hydroxyphenylglycine; -hydroxyphenylglycine, salann monosodium, (R) -isomer; Dp-hydroxyphenylglycine; L-4-hydroxyphenylglycine;oxfenicine;p-hydroxyphenylglycine; RA 25842; RA-25842
Seilbh ceimigeach D(-)-4-Hydroxyphenylglycine
● Coltas/Dath: pùdar neo-gheal
● Brùthadh vapor: 0.000272mmHg aig 25 ° C
● Puing leaghaidh: 240 ° C (dec.) (lit.)
● Clàr-innse ath-tharraingeach: -158 ° (C = 1, 1mol / L HCl)
● Rubha Goil: 365.8 ° C aig 760 mmHg
● PKA: 2.15 ± 0.10 (Air a ro-innse)
● Puing Flash: 175 ° C
● PSA: 83.55000
● Dùmhlachd: 1.396 g/cm3
● LogP: 1.17690
● Storage Temp.:Store gu h-ìosal +30 ° C.
● Solubility.: 5g/l
● Solubility uisge.: 5 g/L (20ºC)
● XLogP3:-2.1
● Cunnt Tabhartas Bond Hydrogen:3
● Cunnt Glacadair Bond Hydrogen:4
● Cunnt Bond Rotatable:2
● Dìreach Aifreann: 167.058243149
● Cunnt Atom Trom: 12
● Iom-fhillteachd: 164
Purity / Càileachd
99% * dàta bho sholaraichean amh
4-Hydroxy-D-(-)-2-phenylglycine * dàta bho sholaraichean ath-bheachdan
Fiosrachadh Sàbhailteachd
● Dealbh(an):
Xi
● Còdan Cunnart: Xi
● Aithrisean: 36/37/38
● Aithrisean Sàbhailteachd: 26-36-24/25
Faidhlichean MSDS
Feumail
● Canonical SMILES: C1=CC(=CC=C1C(C(=O)O)N)O
● SMILES Isomeric: C1=CC(=CC=C1[C@H](C(=O)O)N)O
● A’ cleachdadh: 4-Hydroxy-D-(-)-2-phenylglycine is a compound a thathar a’ cleachdadh sa mhòr-chuid airson ullachadh synthetigeach de antibiotaicean β-lactam.Tha 4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A (Amoxicillin EP Impurity A)) na stuth a thathas a’ cleachdadh sa mhòr-chuid airson ullachadh synthetigeach de antibiotaicean β-lactam.
Tha 4-Hydroxy-D-phenylglycine, ris an canar cuideachd 4-hydroxy-D-phenylglycine no 4-HDPG, na todhar ceimigeach leis an fhoirmle moileciuil C8H9NO3.Is e derivative aminoideach a th’ ann agus buinidh e don roinn de phenylglycines.4-Hydroxy-D-phenylglycine air a chleachdadh sa mhòr-chuid mar bhloc togail ann an synthesis todhar cungaidh-leigheis.Tha e na stuth amh ann an cinneasachadh antibiotics sònraichte, leithid cefadroxil agus cephradine.Buinidh na antibiotaicean sin don chlas cephalosporin agus tha iad air an cleachdadh airson galairean bactaraidh a làimhseachadh.Tha rannsachadh a 'moladh gum faodadh buaidhean antioxidant agus anti-inflammatory a bhith aige, a dh' fhaodadh a dhèanamh feumail ann a bhith a 'leasachadh dhrogaichean ùra airson diofar shuidheachaidhean meidigeach. cleachdaidhean teirpeach.Tha a dhreuchd mar bhloc togail ann an cinneasachadh antibiotics a’ soilleireachadh cho cudromach sa tha e ann an gnìomhachas cungaidh-leigheis.
