Bathar
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Synonyms: 4(1H) -Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-aon; 2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol;2,6-Diaminopyrimidin-4-aon;2,6-Diaminopyrimidine-4(3H) -aon;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Seilbh Ceimigeach de 2,4-Diamino-6-hydroxypyrimidine
● Coltas/Dath: geal cruaidh
● Brùthadh vapor: 0.00232mmHg aig 25 ° C
● Puing leaghaidh: 285-286 ° C (dec.) (lit.)
● Clàr-innse refractive: 1.7990 (tuairmse)
● Rubha Goil: 288.5 ° C aig 760 mmHg
● PKA: 10.61 ± 0.50 (Air a ro-innse)
● Puing Flash: 128.3 ° C
● PSA: 98.05000
● Dùmhlachd: 1.84 g/cm3
● LogP: 0.50900
● Teòthachd stòraidh.:Desiccate aig +4°C
● Mothachail.: Mothachadh aotrom
● Solubility.:DMSO (beagan), Methanol (Beag)
Purity / Càileachd
99% * dàta bho sholaraichean amh
2,4-Diamino-6-hydroxypyrimidine * dàta bho sholaraichean ath-bheachdan
Fiosrachadh Sàbhailteachd
● Dealbh(an):
Xi
● Còdan Cunnart: Xi
● Aithrisean: 36/37/38
● Aithrisean Sàbhailteachd: 22-24/25-36-26
Faidhlichean MSDS
Feumail
● Tuairisgeul: Tha 2,4-Diamino-6-hydroxypyrimidine (DAHP) na neach-dìon sònraichte roghnach de GTP cyclohydrolase I, an ceum cuibhreachaidh reata airson synthesis de novo pterin.Ann an ceallan HUVEC, tha an IC50 airson casg air biosynthesis BH4 timcheall air 0.3 mM.Faodar DAHP a chleachdadh gus casg a chuir air cinneasachadh NO ann an grunn sheòrsaichean cealla.
● A’ cleachdadh: Tha 2,4-Diamino-6-hydroxypyrimidine (DAHP) na neach-dìon roghnach, sònraichte de GTP cyclohydrolase I, an ceum cuibhreachaidh reata airson synthesis de novo pterin.Ann an ceallan HUVEC, tha an IC50 airson casg air biosynthesis BH4 timcheall air 0.3 mM.Faodar DAHP a chleachdadh gus casg a chuir air cinneasachadh CHAN EIL gu h-èifeachdach ann an grunn sheòrsaichean cealla. Tha 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) na todhar a tha feumail ann an synthesis organach.
Tha 2,4-Diamino-6-hydroxypyrimidine na todhar ceimigeach leis an fhoirmle moileciuil C4H6N4O.Tha e air a chleachdadh gu cumanta mar eadar-mheadhanach ann an synthesis diofar choimeasgaidhean, a’ gabhail a-steach drogaichean cungaidh-leigheis agus dathan.Tha structar fàinne pyrimidine aig an todhar anns a bheil dà bhuidheann amino (NH2) agus aon bhuidheann hydroxyl (OH) ceangailte ri diofar dadaman gualain.Tha an structar seo ga dhèanamh na bhloc togail ioma-ghnìomhach airson synthesis de mholacilean nas iom-fhillte.2,4-Diamino-6-hydroxypyrimidine gheibhear le diofar dhòighean synthetigeach, a’ toirt a-steach freagairt cyanamide le urea.Tha grunn thagraidhean aige ann an gnìomhachas cungaidh-leigheis, gu sònraichte ann an synthesis dhrogaichean anticancer agus antibiotics.Overall, tha 2,4-Diamino-6-hydroxypyrimidine na todhar cudromach a lorgas goireasachd ann an grunn thagraidhean ceimigeach agus cungaidh-leigheis.
